Gene information
Official symbol CYP3A5
Official full name cytochrome P450 family 3 subfamily A member 5
Gene type protein-coding gene
Chromosome7q22.1
Alias symbolPCN3; P450PCN3; CP35
Gene familyCytochrome P450 family 3
Resources
Entrez Gene 1577
HGNC HGNC:2638
Ensembl ENSG00000106258
Vega OTTHUMG00000156724
UCSC uc003urq.4
GO terms: 30 records
GO Description Category LogP Number of genes Detail
GO:0001523 retinoid metabolic process GO Biological Processes -3.75216665 12 More
GO:0004497 monooxygenase activity GO Molecular Functions -11.8172125 15 More
GO:0005506 iron ion binding GO Molecular Functions -10.4063739 16 More
GO:0006066 alcohol metabolic process GO Biological Processes -16.7128396 29 More
GO:0006720 isoprenoid metabolic process GO Biological Processes -5.01065294 9 More
GO:0006721 terpenoid metabolic process GO Biological Processes -4.89883771 15 More
GO:0006805 xenobiotic metabolic process GO Biological Processes -8.19045514 12 More
GO:0008202 steroid metabolic process GO Biological Processes -19.3229835 29 More
GO:0008395 steroid hydroxylase activity GO Molecular Functions -9.29772341 9 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0010817 regulation of hormone levels GO Biological Processes -29.5190556 49 More
GO:0016101 diterpenoid metabolic process GO Biological Processes -3.60396371 12 More
GO:0016491 oxidoreductase activity GO Molecular Functions -14.1519969 39 More
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO Molecular Functions -11.3284001 18 More
GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO Molecular Functions -13.5752504 12 More
GO:0020037 heme binding GO Molecular Functions -15.4577568 20 More
GO:0030258 lipid modification GO Biological Processes -3.55367288 9 More
GO:0032787 monocarboxylic acid metabolic process GO Biological Processes -19.1871601 38 More
GO:0034308 primary alcohol metabolic process GO Biological Processes -3.85295720 7 More
GO:0042178 xenobiotic catabolic process GO Biological Processes -7.90595898 7 More
GO:0042445 hormone metabolic process GO Biological Processes -9.53279610 17 More
GO:0042572 retinol metabolic process GO Biological Processes -3.60984508 9 More
GO:0044270 cellular nitrogen compound catabolic process GO Biological Processes -1.37456717 8 More
GO:0046906 tetrapyrrole binding GO Molecular Functions -14.8570803 20 More
GO:0070330 aromatase activity GO Molecular Functions -7.90595898 7 More
GO:0070988 demethylation GO Biological Processes -3.87651549 6 More
GO:0070989 oxidative demethylation GO Biological Processes -7.19780504 6 More
GO:0071466 cellular response to xenobiotic stimulus GO Biological Processes -9.33788411 28 More
GO:0120254 olefinic compound metabolic process GO Biological Processes -12.8805599 18 More
GO:1901615 organic hydroxy compound metabolic process GO Biological Processes -22.7091625 41 More
KEGG pathways: 4 records
KEGG Description Category LogP Number of genes Detail
hsa00140 Steroid hormone biosynthesis KEGG Pathway -2.22481389 4 More
hsa00980 Metabolism of xenobiotics by cytochrome P450 KEGG Pathway -5.38623088 8 More
hsa00982 Drug metabolism - cytochrome P450 KEGG Pathway -7.86918833 10 More
hsa05204 Chemical carcinogenesis - DNA adducts KEGG Pathway -6.89688307 9 More
Drug-Gene interaction
view
Related drugs: 103 records
Drug name Interaction type Source PMID View
alprazolam PharmGKB 18695978 view
amiodarone PharmGKB 18695978 view
amlodipine PharmGKB 17178265 view
amprenavir NCI 16433896 view
apixaban PharmGKB 2867804929457840 view
artemether PharmGKB view
atorvastatin PharmGKB 161038961590021518727922186959781728939715284534 view
atropine NCI 2128054 view
axitinib PharmGKB 24433361 view
boceprevir PharmGKB view
buprenorphine PharmGKB 18695978 view
buspirone PharmGKB 18695978 view
carbamazepine NCIPharmGKB 12673034243845572173808118695978254954092642149123252947 view
carboplatin PharmGKB 26179145 view
celecoxib PharmGKB 18695978 view
chlorpheniramine PharmGKB 18695978 view
cilostazol PharmGKB view
citalopram PharmGKB 18695978 view
clarithromycin PharmGKB 18695978 view
clindamycin PharmGKB 18695978 view
clopidogrel DTCPharmGKB 2182826320938371 view
cobicistat inhibitor ChemblInteractions view
cyclobenzaprine PharmGKB 18695978 view
cyclosporine NCI 12673034 view
dabigatran PharmGKB 32564268 view
diazepam PharmGKB 18695978 view
docetaxel PharmGKB 21151855 view
dolutegravir PharmGKB view
donepezil PharmGKB 18695978 view
efavirenz PharmGKB 2086046320625352244772231626776415622315 view
erythromycin PharmGKB 18695978 view
esomeprazole PharmGKB 18695978 view
eszopiclone PharmGKB 18695978 view
everolimus PharmGKB 2645830124628014 view
fenofibrate PharmGKB 18695978 view
fentanyl PharmGKB 2227767830281924243659892723664018695978 view
fluoxetine PharmGKB 18695978 view
fluvastatin PharmGKB view
gefitinib NCI 17575239 view
granisetron PharmGKB 27809336 view
haloperidol PharmGKB 2702343718695978 view
hydrocodone PharmGKB 18695978 view
hydromorphone PharmGKB 18695978 view
hydroxyzine PharmGKB 18695978 view
imatinib PharmGKB 27426203 view
isopropyl alcohol NCI 6409434 view
isotretinoin PharmGKB 18695978 view
lansoprazole PharmGKB 18695978 view
lapatinib DTC 2340437322511346 view
lopinavir PharmGKB view
loratadine PharmGKB 18695978 view
losartan PharmGKB 18695978 view
lovastatin PharmGKB 1869597815284534 view
lumefantrine PharmGKB view
medroxyprogesterone acetate PharmGKB 18695978 view
meloxicam PharmGKB 18695978 view
meperidine PharmGKB 18695978 view
midazolam PharmGKB 24214410259792622898660623327575 view
mirtazapine PharmGKB 18695978 view
modafinil PharmGKB 18695978 view
montelukast PharmGKB 18695978 view
nevirapine PharmGKB 200176691922820521824325 view
nifedipine PharmGKB 22875663 view
nimodipine PharmGKB 19205682 view
olanzapine PharmGKB 23559402 view
omeprazole PharmGKB 18695978 view
ondansetron PharmGKB 21596874 view
oxycodone PharmGKB 1869597821209234 view
paclitaxel NCIPharmGKB 261791451675300520212519 view
pantoprazole PharmGKB 18695978 view
paroxetine PharmGKB view
phenytoin NCI 12673034 view
pioglitazone PharmGKB 18695978 view
prasugrel PharmGKBFDA 21828263 view
prednisolone NCI 12673034 view
progesterone PharmGKB 18695978 view
propoxyphene PharmGKB 1869597820133509 view
quetiapine PharmGKB 2424048018695978 view
rifampin DTCPharmGKB 1869597826291341 view
ritonavir inhibitor PharmGKB view
rosuvastatin PharmGKB 20207952 view
salmeterol PharmGKB 18695978 view
sertraline PharmGKB 18695978 view
sibutramine PharmGKB 18695978 view
sildenafil PharmGKB 18695978 view
simvastatin NCIPharmGKB 2459871823252946171925061869597817289397261647211632162115284534 view
sirolimus PharmGKB 1681531717941052265437712824518722094953262566741570741523974086 view
sufentanil PharmGKB 31773688 view
sunitinib PharmGKB 2201505724013576 view
tadalafil PharmGKB 18695978 view
tamsulosin PharmGKB 18695978 view
terazosin PharmGKB 18695978 view
tesmilifene TdgClinicalTrial view
tramadol PharmGKB 18695978 view
trazodone PharmGKB 18695978 view
tretinoin PharmGKB 18695978 view
triazolam PharmGKB view
vardenafil PharmGKB 21934637 view
venlafaxine PharmGKB 18695978 view
vincristine PharmGKB view
warfarin PharmGKB 18695978 view
ziprasidone PharmGKB 18695978 view
zolpidem PharmGKB view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_000777.5:c.219-237A>G genomics rosuvastatin[treatment (pharmacotherapy)] acute myocardial infarction Bailey KM et al. Circ Cardiovasc Genet. 2010
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